鑱婂煄鎬х梾閱�(y墨)闄�
婵卞窞鎬х梾閱�(y墨)闄�
鑿忔兢鎬х梾閱�(y墨)闄�
寰峰窞鏁村舰缇庡閱�(y墨)闄�
鏅鐢风閱�(y墨)闄�
濞佹捣鎬х梾閱�(y墨)闄�
婵熷鎬х梾閱�(y墨)闄�
鏃ョ収鎬х梾閱�(y墨)闄�
钀婅暘鎬х梾閱�(y墨)闄�
婵熷崡鍏掔閱�(y墨)闄�
婵卞窞绮剧閱�(y墨)闄�
鑿忔兢绮剧閱�(y墨)闄�
濞佹捣鍏掔閱�(y墨)闄�
婵熷鍏掔閱�(y墨)闄�
鏃ョ収鍏掔閱�(y墨)闄�
钀婅暘鍏掔閱�(y墨)闄�
寰峰窞鍏掔閱�(y墨)闄�
鑱婂煄鍏掔閱�(y墨)闄�
婵卞窞鍏掔閱�(y墨)闄�
鑿忔兢鍏掔閱�(y墨)闄�
婵熷崡濠︾敘(ch菐n)閱�(y墨)闄�
鏃ョ収绮剧閱�(y墨)闄�
钀婅暘绮剧閱�(y墨)闄�
寰峰窞绮剧閱�(y墨)闄�
鑱婂煄绮剧閱�(y墨)闄�
濞佹捣鐧界櫆棰ㄩ啱(y墨)闄�
婵熷鐧界櫆棰ㄩ啱(y墨)闄�
鏃ョ収鐧界櫆棰ㄩ啱(y墨)闄�
钀婅暘鐧界櫆棰ㄩ啱(y墨)闄�
鑱婂煄鐧界櫆棰ㄩ啱(y墨)闄�
閬╃敤浜庝績閫插眬閮ㄨ娑插惊鐠�(hu谩n)銆佽紨鍔╂秷鐐庛€佹秷鑵拰姝㈢棝銆傞仼鐢ㄤ簬灏嶉牳妞庣梾銆佽偐鍛ㄧ値銆侀璩鐢熴€佽叞妞庨枔鐩ょ獊鍑恒€侀棞绡€(ji茅)鐐庛€佽倢绾栫董鐐庛€佽粺绲勭箶鎵尗鍌枫€佹€ユ€ц叞鑲屽嫗鎼嶇殑杓斿姪娌荤檪銆傞仼鐢ㄤ簬绶╄В鑵块儴闂滅瘈(ji茅)銆佽倢鑲夌柤鐥涘強鑲遍澶栦笂楂佺値寮曡捣鐨勯棞绡€(ji茅)婊戣啘鐐庢墍鑷翠箣鐤肩棝銆�
閹�(zh猫n)鍜筹紝绁涚棸锛屽钩鍠橈紝娑堢値銆傜敤浜庡挸鍠樺強鎱㈡€ф敮姘ｇ鐐庡挸鍡姐€�
1.鍘熺櫦(f膩)鎬ч珮鑶藉浐閱囪鐧ユ湰鍝佷綔鐐洪２椋熸帶鍒朵互澶栫殑杓斿姪娌荤檪,鍙柈鐛ㄦ垨鑸嘓MG-CoA閭勫師閰舵姂鍒�(浠栨眬椤�)鑱�(li谩n)鍚堟噳鐢ㄤ簬娌荤檪鍘熺櫦(f膩)鎬�(闆滃悎瀛愬鏃忔€ф垨闈炲鏃忔€�)楂樿喗鍥洪唶琛€鐧ワ紝鍙檷浣庣附鑶藉浐閱�(TC)銆佷綆瀵嗗害鑴傝泲鐧借喗鍥洪唶(LDL-C)銆佽級鑴傝泲鐧紹(ApoB)銆� 2.绱斿悎瀛愬鏃忔€ч珮鑶藉浐閱囪鐧�(HoFH)鏈搧鑸囦粬姹€椤炶伅(li谩n)鍚堟噳鐢紝鍙綔鐐哄叾浠栭檷鑴傛不鐧傜殑杓斿姪鐧傛硶(濡侺DL-C琛€婕垮垎闆㈢疆鎻涙硶)锛屾垨鍦ㄥ叾浠栭檷鑴傛不鐧傜劇鏁堟檪鐢ㄤ簬闄嶄綆HoFH鎮ｈ€呯殑TC鍜孡DL-C姘村钩銆� 3.绱斿悎瀛愯胺鐢鹃唶琛€鐧�(鎴栨鐗╃斁閱囪鐧�)鏈搧浣滅偤椋查鎺у埗浠ュ鐨勮紨鍔╂不鐧傦紝鐢ㄤ簬闄嶄綆绱斿悎瀛愬鏃忔€ц胺鐢鹃唶琛€鐧ユ偅鑰呯殑璋风斁閱囧拰妞嶇墿鐢鹃唶姘村钩銆�
瑗垮湴閭ｉ潪閬╃敤浜庢不鐧傚媰璧峰姛鑳介殰绀欍€�
1.瀛ｇ瘈(ji茅)鎬ч亷鏁忔€ч蓟鐐庨仼鐢ㄤ簬绶╄В鎴愪汉鍜�6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑瀛ｇ瘈(ji茅)鎬ч亷鏁忔€ч蓟鐐庣浉闂滅殑鐧ョ媭锛屽鎵撳櫞鍤忥紝娴侀蓟娑曪紝榧汇€佽叚銆佸枆閮ㄧ櫦(f膩)鐧€€佺溂鐫涚櫦(f膩)鐧€€佹疆婵曘€佺櫦(f膩)绱呫€� 2.鎱㈡€х壒鐧�(f膩)鎬ц晛楹荤柟閬╃敤浜庢不鐧傛垚浜哄拰6姝插強6姝蹭互涓婂勾榻″厭绔ョ殑鎱㈡€х壒鐧�(f膩)鎬ц晛楹荤柟鐨勭毊鑶氱櫏鐙€锛岃兘澶犻’钁楁笡杓曠槞鐧㈠拰棰ㄥ湗鐨勬暩(sh霉)閲忋€�
寤ｆ澅缇呮诞灞卞湅钘ヨ偂浠芥湁闄愬叕鍙告槸涓€瀹跺緸浜嬭棩鍝佺敓鐢�(ch菐n),钘ュ搧缍�(j墨ng)鐕�,涓崏钘ユ敹璩肩瓑妤�(y猫)鍕欑殑鍏徃锛屾垚绔嬩簬2008骞�12鏈�24鏃ワ紝鍏徃鍧愯惤鍦ㄥ唬鏉辩渷锛岃┏绱板湴鍧€鐐猴細鎯犲窞甯傚崥缇呯福闀峰閹�(zh猫n)寤ｆ睍鍏矾閭婂逗鎺掑伐妤�(y猫)鍗€(q奴)锛堢緟娴北钘ユキ(y猫)鍩庯級;缍�(j墨ng)鍦�
鍖椾含闊撶編钘ュ搧鏈夐檺鍏徃(浠ヤ笅绨＄ū鍖椾含闊撶編)鎴愮珛浜�1996骞�3鏈堬紝鍏徃鐢�(ch菐n)鍝佹キ(y猫)鍕欐秹鍙婂厭绉戠敘(ch菐n)鍝併€佹秷鍖栫鐢�(ch菐n)鍝併€侀绉戠敘(ch菐n)鍝併€佹姉鎰熸煋钘ョ瓑闋樺煙锛�98%鐨勭敘(ch菐n)鍝佸湪鍦嬪収鎴愮敘(ch菐n)锛屼富瑕佺敘(ch菐n)鍝佹湁濯藉挭鎰涖€佹槗鍧﹂潨銆佹槗瀹夊钩銆佺編甯稿畨銆佸埄鍕曘€�
銆€銆€鐩婃櫘鐢熼泦鍦樹綔鐐轰竴瀹舵湁钁楀叓鍗佸骞村埗钘ョ稉(j墨ng)椹楃殑姝愭床鍒惰棩闆嗗湗锛屾搧鏈�20浣欑ó涓婂競鐢�(ch菐n)鍝佸強閬嶅竷鍏ㄧ悆杩�4000鍚嶇殑鍝″伐銆傚叕鍙哥殑鐧�(f膩)灞曟埌(zh脿n)鐣ユ槸浠ヤ笁澶ф不鐧傞牁鍩熷収鐨勯珮绉戞妧鐢�(ch菐n)鍝佺偤鍩虹锛屽嵆鑵槫銆佸収鍒嗘硨銆佺缍�(j墨ng)鑲岃倝椤炵柧鐥咃紝閫欎簺楂�
鍖椾含鍚屼粊鍫傝偂浠芥湁闄愬叕鍙稿悓浠佸爞鍒惰棩寤犳垚绔嬩簬1990骞�11鏈�21鏃ワ紝娉ㄥ唺鍦颁綅浜庡寳浜競澶ц垐鍗€(q奴)涓棞鏉戠鎶€鍦掑崁(q奴)澶ц垐鐢熺墿閱�(y墨)钘ョ敘(ch菐n)妤�(y猫)鍩哄湴澶╄泊澶ц33铏燂紝娉曞畾浠ｈ〃浜虹偤寮垫湞鑿€傜稉(j墨ng)鐕熻寖鍦嶅寘鎷姞宸ャ€佸埗閫犱腑鎴愯棩锛涘嚭绉熻睛鍏敤鎴�
杓濈憺鍦ㄤ腑鍦嬫キ(y猫)鍕欒钃嬪叏鍦�300浣欏€嬪煄甯傦紝骞跺湪鑿笂甯備簡浜斿ぇ闋樺煙鐨勯珮鍝佽唱鐨勫壍(chu脿ng)鏂拌棩鐗╋紝鍖呮嫭鑵槫銆佺柅鑻椼€佹姉鎰熸煋銆佺値鐧ヨ垏鍏嶇柅銆佺綍瑕嬬梾绛夊鍊嬮牁鍩熺殑铏曟柟钘ュ拰鐤嫍銆傚骞翠締锛岃紳鐟炲绲傝嚧鍔涗簬鈥滄垚鐐轰腑鍦嬮啱(y墨)鐧傝(w猫i)鐢熼珨绯婚噸瑕佺祫鎴�
